We provide our partners a unique package for commercial manufacturing and development of Active Ingredients via plant cell fermentation and other expression systems.

Large Scale Fermentation

• 880.000 L/year production capacity for taxanes
• HPAPI handling
• cGMP compliant process
• Fermentation trains
  • 2 prefermentation areas (one BSL 1 classified)
  • 9 fermenters 55 L to 75.000 L
  • 4 fermenters 75 L to 7.500 L (BSL 1 classified)
  • Strain bank storage

Process Development

• 12 parallel 16 L fermenters (in BSL 1 area)
• Multiple incubator cabinets for shake flask cultivations
• Miniaturized cultivation systems in well plate format for screening experiments
• Cryopreservation and cell bank operation
• Product isolation and purification (resin adsorption, biomass separation, static and dynamic filtration processes)

GMP compliant Analytics and Quality Control

• Comprehensive set of optimised IPCs
• Analytical method development
• Production control experiments

Markets

• Pharmaceuticals
• Cosmeceuticals
• Nutraceuticals
• Biopharmaceuticals